Seattle BioMed scientists, Alexis Kaushansky, PhD, Alyse Douglas, and Heather Kain, release research, indicating that two families of cancer drugs successfully target the recurring malaria parasite, Plasmodium falciparum. >>More

Seattle BioMed scientists identify the critical importance of a new tool for malaria research. The human-liver chemiric mouse model could transform the search for drugs and vaccines against relapsing infections from Plasmodium vivax malaria. >>More

Aitchison Op-ed

As the debate about the validity of vaccines and the concerns about the ripple effect of non-vaccination highten, Scientific Director John Aitchison, PhD discusses the critical importance of vaccines in a Puget Sound Business Journal op-ed. >>More

Principal Investigator Stefan Kappe and his lab lead a GAP3KO trial for a potential malaria vaccine candidate. If the trial is succesful, it may lead to a fundamentally different type of malaria vaccine. >>More

While at Seattle BioMed, Dr. Leo Stamatatos and his research team discovered an HIV vaccine candidate that stimulates the production of neutralizing antibodies that defend against infection from a broad spectrum of HIV strains. >>More

Professor John Aitchison is a co-recipient of a $10.9 million grant from the NIH’s Institute of General Medical Sciences to establish a new Biotechnology Resource to aid researchers in interpreting complex biological systems, such as cancer and infectious diseases.   >> More

Novel Agents Capable of Killing TB Identified

Researchers in the lab of Professor David Sherman, Ph.D., have developed and screened several compounds with antibacterial properties capable of destroying Mycobacterium tuberculosis (Mtb), the bacterium that causes TB. These compounds, called anti-folates, block the folate pathway, which is responsible for the synthesis of the essential cellular building blocks, without which Mtb cannot survive. The results of this study were published in the June issue of the journal Chemistry and Biology.  More >>

Collaboration and Systems Biology Needed for Scientific Discovery

In December's issue of Infecious Disease News, Scientific Director John Aitchison, PhD and CFO Louis Coffman discuss the importance of a systems biology approach to infectious disease research. This comprehensive study of interactions coupled with frequent collaboration is key in the discovery and development of lifesaving vaccines and drugs. >>More

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May 14, 2015
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